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DOI:10.1002/cncr.28654 [ Links ] 36

Agarwal, P

Epilepsia 2009;50:304317

For example, cocaine may activate microglia by downregulating miR-124 targeting kruppel-like factor 4 and toll-like receptor 4 signaling, which may contribute to cocaine-induced synaptic plasticity (170, 171)

These findings suggest that ALC may reduce de novo cholesterol synthesis by inhibiting SREBP2, leading to decreased HMGCR levels and subsequently lowering cholesterol