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Conversely, A431 cells, with lower TGF1 secretion and basal HO-1 expression, show greater sensitivity to PDT when isolated but are more susceptible to develop resistance when exposed to exogenous TGF1, a response that is likely mediated by the induction of cell cycle arrest

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This delay in reaching the maximal concentration compared with term neonates primarily reflects the delay in maturation of hepatic UGT activity

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Phillips RD, Wallace Hayes A, Berndt WO, Williams WL (1980) Effects of citrinin on renal function and structure