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Sarris AH, Kliche KO, Smith T, Preti A, Messina O, Hess M, Pugh W, Andreeff M , Cabanillas F

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[85] reported that inhibiting Hedgehog signaling enhances O-GlcNAcylation of the transcription factors Foxp3 and STAT3, thereby driving Treg cells toward a Th17-like phenotype