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The impact of proton pump inhibitors on the human gastrointestinal microbiome

They may however lead to calcium overload (46,47) and excessive PTH suppression, resulting eventually in adynamic bone disease (319)

G.JuangT.-Y.WangT.-F

however, these interactions seem to depend on the presence of ROS and the receptors redox state, rather than occurring under typical physiological conditions [5,8]