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Dihydroartemisinin inhibits the activation of the NF-B signaling pathway, reduces the expression of inflammatory factors (TNF- and IL-6), and decreases leukocyte counts for the treatment of radiation pneumonitis induced by A6MV-X-rays ( Excessive production of inflammatory factors can lead to lung damage ( 5.1.2 Antioxidant potential Extensive results carried out show that artesunate and dihydroartemisinin ameliorate oxidative stress in hyperoxia-induced and lipopolysaccharides (LPS)-induced lung injury in a dose-dependent manner, these compounds may increase nuclearrespiratoty factor 2 (Nrf2) levels in reactive oxygen species (ROS)-sensitive cells

It supports multiple functions in human metabolism, including cellular metabolism in the brain

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Epub 2021 Aug 4