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196 In summary, a reciprocal regulatory loop exists between BMAL1 and HIF-1, wherein BMAL1 modulates both the activity and transcription of HIF-1, while HIF-1 in turn regulates BMAL1 expression and circadian rhythm

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Abstract Graft-versus-Host Disease (GvHD) is the main cause of morbidity and mortality of allogeneic hematopoietic cell transplantation (allo-HCT)

[5] Hence SAM synthetase is fast becoming a drug target, in particular for the following diseases: depression, dementia, vacuolar myelopathy, liver injury, migraine, osteoarthritis, and as a potential cancer chemopreventive agent

Ellagic acid ameliorates hexavalent chromium-induced renal toxicity by attenuating oxidative stress, suppressing TNF- and protecting mitochondria