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C: Group 3 retrograde nerve reinnervation with S-100 staining, showing evidence of the epineurium, perineurium, and endoneurium

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Taken together, these results suggest that Ssu72 induces adipogenesis and lipogenesis in white adipocytes by GSK3/-catenin axis under HFD conditions, contributing to adipose tissue expansion during diet-induced obesity

At the FD location, a thicker epineurium and reduced echogenicity of the inner nerve structure were observed, consistent with Wallerian degeneration 3, 5