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in obese murine models exposed to the peptide for approximately three weeks suggested that any gain in overall mass was estimated to be cut in half compared to placebo controls

Figure 4 Macrophages are the key mediators by which monoclonal antibodies to play a therapeutic role, and antibodies targeting CD38 will also affect macrophage function ( Summary and Prospects CD38 has dual functions, acting as an extracellular enzyme and a surface receptor