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In I/R-AKI, N-myc downstream-regulated gene 2 (Ndrg2) deficiency can reduce oxidative stress and delay renal injury by activating PINK1/1Parkin-mediated mitophagy, but the exact mechanism remains to be investigated further[112]

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In another study, it was reported that SOD activity decreased in bladder cancer patients compared to healthy control groups 45

doi: 10.21037/tlcr-21-303 105 HongTLeiGChenXLiHZhangXWuNet al