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Conversely, urate-like antioxidants produced in the hemolymph were found to arrest epimastigotes' growth and promote differentiation of epimastigotes to metacyclic infective form (Nogueira et al., 2015)

PLoS ONE 7(1):e29641

Redox Signal 34 , 324334 (2021)

It is a Schedule II controlled substance with high potential for abuse, dependence, and overdose

53 Additionally, biological assays determine whether they are agonistic or antagonistic compared to the most potent biologically active natural estrogen, 17-estradiol