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It promotes new blood vessel formation, stimulates keratinocyte and fibroblast migration into wound sites, and modulates the inflammatory response by reducing local levels of inflammatory cytokines all critical to healing after oral surgical procedures

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These changes suggest ARA-290 may influence metabolic function through its anti-inflammatory effects, since chronic inflammation contributes significantly to insulin resistance and dyslipidemia

Preclinical studies have described effects on tendon healing, ligament repair, muscle regeneration, and inflammatory modulation (Vasireddi et al