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6 replicates per conditions were performed

LC3 conjugation system in mammalian autophagy

REDEFINE 1 (Phase 3a, NEJM 2025) Garvey et al., n=3,417, 68 weeks

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The important pathways involved in the KEGG pathway were neuroactive ligand-receptor interaction (hsa04080), PI3K-Akt signaling pathway (hsa04151), calcium signaling pathway (hsa04020), cAMP signaling pathway (hsa04024), MAPK signaling pathway (hsa04010), Ras signaling pathway (hsa04014), serotonergic synapse (hsa04726), and pathways of neurodegenerationmultiple diseases (hsa05022), Rap1 signaling pathway (hsa04015) and Alzheimers disease (hsa05010)