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Oncogene (2021) 40:201834

Therefore, NAC treatment could modify the oxidant/antioxidant imbalance in the lungs, potentially reducing respiratory symptoms, exacerbations, and the deterioration of lung function in COPD patients

Fisetin, a natural flavonoid, attenuated DOX-mediated ferroptosis in vivo and in vitro by raising the contents of GSH and GPX4 and inhibiting the accumulation of MDA and iron in the heart of rats [92]