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Moreover, treatment with 10 ng/mL of IGF-1 for 10 days was demonstrated to be sufficient to induce tenogenic differentiation of bone marrow MSCs in 3D in vitro culture with significant upregulation of tenocytic markers (SCX, collagen type III, and decorin) (Durgam et al., 2012)

A systematic evaluation of peripheral cytokines (e.g., via multiplex Luminex assays) will be conducted in follow-up studies to map gut-derived immune signals to CNS pathology

A key aspect of garlics chemistry is the release of alliin from its stable form when the plant is crushed or chopped

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doi: 10.1038/nature11743 10 MaddocksODKAthineosDCheungECLeePZhangTvan den BroekNJFet al