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Restoring clinical euthyroidism required 2 to 3 grains (120 to 180mgs) of DTE, 200 to 400mcgs of T4, or 75 to 125mcgs of T3 (15, 17)

In some cases, patients will need to be seen daily and medications altered depending upon the presentation

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Because activities of creatine-synthesizing enzymes in HSB were upregulated by the dietary intake of glycine, it is crucial that diets must provide sufficient glycine to support creatine synthesis in fish