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As the primary site of energy production through oxidative phosphorylation, mitochondria are also a significant source of ROS

Hou Y, Wang L, Yi D, Ding B, Yang Z, Li J, Chen X, Qiu Y, Wu G (2013) N-acetylcysteine reduces inflammation in the small intestine by regulating redox, EGF and TLR4 signaling

36,189,190 In overweight or obese women with polycystic ovary syndrome, weight loss of 5% or more restored regular ovulatory menstrual cycling within six months in the majority of women