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Based on these different studies, it is possible that the beneficial effect of riluzole may be due to a combined action on different targets that still remain largely unclear

Studies have looked at baseline potassium levels on admission, however there is limited investigation on the effects of discharge potassium levels towards outcomes in cirrhosis patients

doi: 10.1152/physiolgenomics.00127.2010 251 HumbyFDurezPBuchMHLewisMJRizviHRivelleseFet al

Studies have shown that oxidative stress induces endothelial cell apoptosis and disrupts the endothelial glycocalyx, facilitating leukocyte adhesion and extravasation, which worsens tissue damage (Joffre and Hellman, 2021)