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178 Compared with traditional single-target agents, SIRT1 activators simultaneously modulate several critical pathways, including metabolism, immune responses, and oxidative balance, offering a network reprogramming therapeutic advantage, particularly in the early stages of the disease when multiple processes are synergistically dysregulated

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Chalyk NE, Klochkov VA, Bandaletova TY, Kyle NH, Petyaev IM (2017) Continuous astaxanthin intake reduces oxidative stress and reverses age-related morphological changes of residual skin surface components in middle-aged volunteers

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