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"It's possible that mania is a very rare but important side effect of garcinia cambogia and we're just seeing it in susceptible people now that the supplement is so widely used," says Stephen Heymsfield, M.D., a professor at Louisiana State University's Pennington Biomedical Research Center and an expert on garcinia cambogia, who was not involved in the current study

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Medical conditions such as cardiovascular disease, cancers, compromized mental health, and adverse birth outcomes can also be caused by a B 12 deficiency [462, 463]