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Madugundu, Praveen Kumar, Dr

Exclusion criteria consisted of research falling outside the specified time, topics beyond the scope of this review, and unpublished studies, books, conference proceedings, abstracts, and dissertations

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the catalytic core domain contains a trio of amino acids that coordinate binding with a divalent metal cofactor (either Mg2 + or Mn2 + ), and this region forms the active catalytic site (Figure 10).[37,38,39]

Importantly, this design enabled the production of a library of stapled TF analogs derived from the DNA-binding domain (DBD) of Max with selective incorporation of staples at strategic positions in the leucine zipper and the basic domain