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Moreover, the tumor microenvironment (TME) in HCC is enriched with M2-polarized tumor-associated macrophages (TAMs), a dominant immunosuppressive population that promotes NK cell dysfunction and exhaustion [5, 11, 12]

A review on the oxidative and nitrosative stress (O&NS) pathways in major depression and their possible contribution to the (neuro) degenerative processes in that illness

AE rates were high with approximately half of patients reporting at least one AE

Small molecules directly targeting the clock proteins offer the potential to directly manipulate endogenous circadian rhythm to improve clock-regulated output processes, as well as to treat diseases associated with clock misalignment (for a comprehensive review on the topic see 135

However, the protective effects of GA on liver diseases and the underlying mechanisms remain unclear