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Combined use of amlodipine and folic acid are significantly more efficacious than amlodipine alone in lowering plasma homocysteine and blood pressure among hypertensive patients with hyperhomocysteinemia and intolerance to ACEI: A multicenter, randomized, doubleblind, parallelcontrolled clinical trial

In contrast, the N-terminal domains exhibit greater sequence variability and assemble into multiple ring structures that form a large periplasmic vestibule 21,23

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This process reduces the level of ROS, maintains the cellular redox balance, and protects the tumor cells from oxidative damage [219]

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