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Description

Given that both MitoQ and DPI target mitochondrial function, we used the Loewe synergy model, which is particularly suited for evaluating the combined effects of drugs with similar mechanisms of action (36)

Cancers 14 , 5110 (2022)

doi: 10.1158/1078-0432.CCR-14-2437 57

van Beljouw, I

Unlike patient-specific neoantigens, which require individualized immunotherapeutic development 1,2,3 , commonly mutated oncoprotein-derived epitopes presented on class I major histocompatibility complex (MHC) molecules provide an opportunity to target cancer-specific antigens shared across patient populations 4,5