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The claim that "over 75% of patients achieve significant pain relief without surgery" with peptide therapy comes from clinical observations, not controlled trials

However, the evidence for superiority over subcutaneous administration remains unclear, and the increased complexity and discomfort of IM injection discourages its use for most individuals

Biomedicines 11 , 724 (2023)

F35E12.5 ( irg-5 ) was the most significantly up-regulated gene in the data set

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