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Statements Acknowledgments This work was supported by grants from University of PadovaMURST ex-60%. Conflict of interest The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest

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Besides, they found that patients responding to PD-1 treatment have lower levels of MOESIN lactylation than nonresponders, providing a novel idea of targeting Treg cells via anti-lactate approaches in enhancing tumor immunotherapy (Fig

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