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Moreover, only male participants were selected, considering the possibility that data from older females may be affected by the rapid decrease in estrogen or progesterone levels associated with menopause

MuSC Proliferation In aged skeletal muscle, NNMT overexpression is linked to impaired NAD+ salvage, dysregulated SIRT1 activity, and increased muscle stem cell (MuSC) senescence

Secher A, Jelsing J, Baquero AF, Hecksher-Srensen J, Cowley MA, Dalbge LS, et al

Ferroptosis Ferroptosis typically results from disruptions in iron metabolism, lipid peroxidation and decreased glutathione (GSH) levels or inactivation of GSH peroxidase 4 (GPX4) (14)