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In this review, we report 9 clinical studies from 2014 to 2023, including 6 randomized controlled trials (RCTs), 1 non-randomized single arm clinical trial, and 1 case study related to the benefits of ITC on ASD (Table 1)

Another study also showed that CGA effectively inhibits triglyceride accumulation in HepG2 cells [65], and in adipocytes, it was observed that both caffeic acid (CA) and CGA increase the number and activity of mitochondria [66]

However, the authors emphasized the need for further studies to establish the safety of exogenous ketone supplementation in this population

For a detailed description regarding Se absorption and metabolism, the reader is referred to the specialized reviews, e.g., Roman et al

Although many factors likely contribute to the development of Sjgren syndrome, studies have found strong links between Sjgren syndrome and cytomegalovirus (CMV) a common virus to which about half of Americans have been exposed (Kurien 2017