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It is well established that dental plaque biofilm, harboring periodontopathogens like Porphyromonas gingivalis , serves as a constant inflammatory trigger [20, 21]

Heme iron in animal products is better absorbed

*These statements have not been evaluated by the FDA

Preclinical studies show no significant toxicity at therapeutic doses, with treated animals displaying no adverse behavioral changes or organ dysfunction

Additionally, the degree of endothelial senescence positively correlated with the level of expression of two surface molecules linked to vascular disease, the intracellular adhesion molecule-1 and type 1 plasminogen activation inhibitor (Xu et al, 2000)