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10.1016/j.intimp.2019.105979 42 HalimiJ

In TCA group, mean improvement was 4.0 11.6% with range of 060% while in the methoxsalen group, mean improvement was 0.57 3.3% with range of 020% ( p = 0.051)

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Contributing factors include inaccurate labeling, unknown or variable composition, lack of standardization, substandard quality, contamination, adulteration, inappropriate use, and fraudulent practices