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This review consolidates recent findings indicating that FOXO4-dependent senescence significantly contributes to neuroinflammation, synaptic dysfunction, and impaired neurogenesis in the aging brain

A progressive structural understanding of the detailed receptor-ligand interactions is paving the way for fragment-to-lead optimization in structure-based drug design (SBDD) (Fig

10 Focus on natural products in assisted reproductive technology DOR-associated infertility is primarily linked to a reduction in both the number and quality of oocytes, which significantly limits a womans ability to conceive (Steiner et al., 2017)

After the final heat-shock at 65 C the samples were centrifuged at 20,000 g and 4 C for 10 min