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1h,i) and sensitized MYC-driven cells to DNA-damaging agents, which was rescued by supplementation of KG (Extended Data Fig

A comparative study between African Americans and rural South Africans demonstrated that compared to a diet high in animal protein and fat, a high-fiber, low-fat diet significantly increases butyrate production, inhibits SBAs synthesis (such as DCA), and reduces inflammation and hyperplasia of the colon mucosa, which is associated with the prevention of CRC (O'Keefe et al., 2015)

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