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A.), 317333 (Elsevier, 2014)

The combination creates a dual mechanism: naltrexone reduces food reward and craving intensity, while bupropion enhances the brain's satiety signals and provides mild stimulant-like appetite suppression

Signs of B12 deficiency, such as fatigue, weakness, numbness or tingling in the hands and feet, difficulty walking, memory loss, and mood changes, should not be overlooked