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Following successful model induction, the Uricase and RBC@SeMSN@Uri groups received intravenous injections of 10 mg/kg Uricase or RBC@SeMSN@Uri at 0 h, coinciding with the cessation of fructose feeding

Intestinal epithelial cells primarily degrade Trp via the kynurenine pathway, which is essential for regulating colonic inflammation and colorectal cancer [114]

Role of prostacyclin versus peroxisome proliferator-activated receptor beta receptors in prostacyclin sensing by lung fibroblasts

In addition to the direct effects of altered glutamine consumption on the function of immune cells and glutamine metabolism in the TME, the functional changes in the tumor cells themselves also directly affects the anti-tumor response

It is produced naturally in the body, mainly in the liver where it is synthesised from its precursor amino acids