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The surge in cAMP activates protein kinase A (PKA), which in turn increases the expression of the transcription factor MITF, the master regulator of melanogenesis

Esto ha generado un creciente inters en la investigacin sobre sus efectos reguladores metablicos, en particular en modelos que examinan la obesidad, la tolerancia a la glucosa y la homeostasis lipdica

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There is some controversy in the dermatology community as to whether or not the "dysplastic" or "atypical" nevus exists