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Increased expression of tight junction proteins was a mechanism by which progesterone and estrogen facilitated wound healing and epithelial barrier function in intestinal epithelial cells, as reported using 2D cell lines and IBD patient-derived inflammatory organoid models (252)

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This is when people start saying "I can actually move my shoulder again" or "my knee doesn't lock up on stairs anymore." Real structural healing , tendon remodeling, tissue regeneration, the stuff that actually fixes the problem long-term , takes 4-6 weeks minimum