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Description

Most community protocols use a 24-week staggered titration to reach maintenance, then run open-ended at maintenance with periodic re-evaluation

It is also involved in the synthesis of DNA, which is crucial for the normal functioning of cells, particularly in the nervous system

doi: 10.1186/s12890-023-02361-3

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5-Amino-1MQ targets the substrate binding site of NNMT the nicotinamide binding pocket competitively inhibiting nicotinamide methylation with an IC50 of 1.2 M under reference assay conditions