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5-lipoxygenase inhibition protects retinal pigment epithelium from sodium iodate-induced ferroptosis and prevents retinal degeneration

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Our data showed that, despite the higher mTORC1 signaling in Gclc -deficient FoB cells, these cells dampened antibody production and could not ensure GC formation following activation in vivo and antibody production in vitro

This directly sensitizes osteoclasts to osteoclastogenic signals and entrains ROS-enhanced expression of cytokines that promote osteoclastic bone resorption.

While this can be incredibly invalidating and frustrating, it helps to understand that their skepticism is often rooted in a lack of institutional training rather than malice