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Figure 3 3.2 Anticancer mechanisms of carotenoids 3.2.1 Pro-oxidant and antioxidant balance Carotenoids are a class of strong antioxidants that scavenge free radicals and reduce DNA damage from oxidative stress, thereby preventing genetic mutations and cancerous lesions ( 3.2.2 Immunomodulatory effect Carotenoids also exert anticancer effects through immunomodulation

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Simultaneous 40 Hz visual and auditory flicker stimulation Mice were habituated daily in a quiet area for 30 min prior to being placed in control or 40 Hz stimulation which consisted of the mice being placed individually in a dark chamber illuminated by a light-emitting diode (LED) bulb (12.5 ms light on/off, 60 W, 40 Hz) and exposed to an auditory tone train of 40 Hz, which speakers (AYL, AC-48073), for 1 h during 3 weeks in a quiet room insulated with sound-proof foam (McMaster-Carr, 5692T49) 18,74