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These novel FSPs, or neoantigens, are the result of impaired MMR and have been observed to stimulate the adaptive immune system of LS patients with cancer and individuals with LS-associated germline mutations without clinical disease by eliciting antigen-specific T cell responses [44]

A case-control study in an eastern Chinese Han population revealed that the B7-H3 promoter region shows significant hypomethylation in AS patients relative to healthy controls, which correlates with elevated mRNA expression levels of B7-H3 in peripheral blood samples

Real-time diagnosis of reactive oxygen species (ROS) in fresh sputum by electrochemical tracing

Fact: They operate through different pathways and actually support each other by protecting and rebuilding tissues simultaneously

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