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Early and progressive impairment of spinal blood flow-glucose metabolism coupling in motor neuron degeneration of ALS model mice

This score effectively predicts both immunotherapy response and drug sensitivity

J Biol Chem 282:2947081, PMID: 17690092 Franco R, Cidlowski JA (2009) Apoptosis and glutathione: beyond an antioxidant

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This mitochondrial respiratory defect likely secondarily impairs MFN1-mediated mitochondrial fusion, potentially through mechanisms involving energy depletion or elevated oxidative stress [52]