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Exogenous sources of ROS also involve the consumption of smoked meat and intake of metal-containing drugs (cyclosporine, bleomycin, gentamycin, and others) (Bhattacharyya et al

F-652, a recombinant fusion protein composed of human IL-22 and IgG2-Fc, targets IL-22R1 on epithelial cells, exerting minimal effects on immune cells and protecting tissues from damage and inflammation while promoting tissue repair [258]

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