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Infantile presentation of Lehman syndrome with multiple lateral meningoceles, dural ectasias, and herniation of conus: a rare case report

To address this, our study employs a semi-mechanistic popPK model to quantify sources of PK variability in IV busulfan exposure among pediatric HCT recipients, and mechanistically characterize GST-mediated metabolic pathways influencing drug disposition

The findings were published in The New England Journal of Medicine in April 2023