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Mitochondria are not stationary organelles but rather dynamic and mobile cellular components

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Lipid peroxidation The mammalian ALOX family, consisting of six members (ALOXE3, ALOX5, ALOX12, ALOX12B, ALOX15 and ALOX15B), plays a tissue- or cell-dependent role in mediating PUFA peroxidation to produce AA/AdA-PE-OOHs, thus causing ferroptosis