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THE NNMT INHIBITOR MECHANISM 5-Amino-1MQ (also referred to as 5-amino-1-methylquinolinium) is a small-molecule organic compound that functions as a potent, selective inhibitor of NNMT (nicotinamide N-methyltransferase)

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Vegans and vegetariansSince B12 is mainly found in animal products, those following plant-based diets often need supplementation

While the NIH does not specify a tolerable upper intake level for vitamin B12, a study published in the JAMA Network Open found that high intakes of vitamin B12, such as from daily supplementation of 25 micrograms or higher, increased the risk of bone fracture [3] [4]

Local sites can become tender with repeated daily injection over weeks