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488 Polymorphisms in TNFAIP3 (A20), a DUB that removes K63-linked ubiquitin chains and adds K48-linked chains to signaling intermediates, are associated with SLE

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Unlike previously tested LRRK2 kinase inhibitors with significant side effects, Vit B12, derivative AdoCobalamin (AdoCb) specifically, exhibits a neuroprotective effect by regulating the activity of LRRK2 kinase (Schaffner et al