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Therefore, due to the large volume of SCT-based clinical trials, with almost half (35) of them conducted since 2019, an in-depth exploration of their protocol, results, and effects is needed to provide the reader with an overview of the recent developments within the field

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Secondly, the amino acid sequence also determines the position of key residues and functional groups on the stapled peptide, influencing bioactivities such as the binding affinity and selectivity towards targeting molecules [26]