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The plasmids are substantially variable between species and strains, both in number and in sequence [Citation9]

Supporting these findings, a large cross-sectional analysis from the Lifelines Cohort (11,000 individuals) demonstrated that NS workers exhibited significantly higher counts of leukocytes, monocytes, lymphocytes, and basophil granulocytes compared to non-shift workers, suggesting that frequent or consecutive NSW may acutely stimulate immune cell mobilization and contribute to systemic inflammation 112