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Should there be concerns regarding the appropriateness of administering medications due to the condition/state of the medication, e.g., expired, makeshift or illegible labels, or the condition/state of health of the newly admitted resident, staff members shall consult with or make arrangements to have the resident examined by a physician or other authorized healthcare provider, or at the local hospital emergency room prior to administering any medications

Gillessen, A., & Schmidt, H

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If they are going to be used they should be made according to a USP monograph or be a component of an approved drug, if no monograph exists it must be on the 503A Bulk List, and it must be manufactured in an FDA registered facility with a proper certificate of analysis

2015 Apr;61(4):347-9 [PubMed] 27257155 Mo L, Liang D, Madden A, Aung AK