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The rationale for the variation in diets between the groups lies in the nature of the intervention: the IF group focused on time-restricted eating, while the control group maintained a more conventional dietary pattern

The effects are felt within hours, not weeks, and we can administer much higher, more therapeutic doses than what can be tolerated orally

Additionally, these samples exhibited brain matrix vacuolization, increased reactive astrocytic and microglial infiltration (arrowhead), and severely congested blood vessels (star)