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I.KovyazinaI

Here is how they can improve your health: 1

This recycling process enhances the overall antioxidant capacity of the body

Following this, BH4 can be recycled back from its oxidized form, dihydrobiopterin, with the help of dihydrofolate reductase using NAD(P)H (182,183)

3.2 Role of TGF- in radiation skin fibrosis TGF- is a cytokine intricately involved in the fibrotic process across various organs and tissues ( 3.2.1 TGF- Signaling and cellular mechanisms in radiation-induced fibrosis TGF- exerts its effects through the activation and proliferation of fibroblasts, leading to ECM accumulation ( TGF- expression is dose-dependent on radiation exposure, binding to its receptors to form a trimeric complex which can lead to tissue fibrosis ( Figure 2 )